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| About site: Animal/Mammals/Cats/Conditions and Diseases/Deafness - Deafness in Dogs and Cats |
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| About site: http://www.lsu.edu/deafness/deaf.htm |
Title: Animal/Mammals/Cats/Conditions and Diseases/Deafness - Deafness in Dogs and Cats Information about the condition, including an article describing the association of congenital deafness with white coat color.
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Genetics_and_the_White_Cat Several articles concerning congenital hearing loss with a focus on the Norwegian Forest Cat.
| The_Pigment_Parade Discussion of the association of impaired hearing with white inheritance and blue eye color.
| Roy_Robinson_on_White_Cats Article by the late Roy Robinson on the association of congenital hearing loss with whiteness and blue eye color.
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Deafness in Dogs & Cats DEAFNESS IN DOGS & CATS  Information on Deafness Prevalence, Causes, & ManagementFor Owners, Breeders, and ResearchersGeorge M. StrainProfessor of NeuroscienceComparative Biomedical SciencesSchool of Veterinary MedicineLouisiana State University
Searchthis site poweredby FreeFind Topics on Deafness Dog breeds with congenital deafness Cat breeds with congenital deafness Prevalence of deafness in dog breeds Causes of sudden onset of deafness Hearing frequency ranges for dogs & other species What is the BAER test? What is the bone stimulation BAER? What about hearing aids? BAER testing sitesComing to LSU for BAER testing?Directions to the LSU School of Veterinary Medicine: If coming from the east on I-10, exit at Acadian (Exit 157B) (Acadian becomes Stanford); stay to the left when it becomes a single lane and turn right onto Highland Road when it ends. After entering the camus gates, take the first left (Nicholson Extension) and turn right onto Nicholson Dr north. Turn left (west) on South Stadium Dr/Skip Bertman Dr at the football stadium. If coming from the west on I-10, exit at Highland/Nicholson (Exit 155A) at the end of the Mississippi River bridge, and follow Nicholson Dr to Skip Bertman Dr; turn right (west).Click here for map.NEWS Book coming soon: Deafness in Dogs and Cats by George M. Strain, to be published in October by CABI Press (paperback £35.00 / $65.00 / €50.00, hardback £75.00 / $145.00 / €105.00, 10% discount available on their web site). Also available through Amazon and other online sources. The gene for white color - piebald - has been identified in the dog on chromosome 20 by Elinor Karlsson et al of the Broad Institute of Harvard and MIT, as the pigmentation gene MITF. Elinor K. Karlsson, I Baranowska, CM Wade, et al. Efficient mapping of mendelian traits in dogs through genome-wide association. Nature Genetics, November 2007, 39 (11): 1321-1328. Published on line. Neither this report, nor the one below, explain yet how the pigmentation genes result in deafness. The gene for merle in the dog has been identified and sequenced: Leigh Anne Clark, Jacquelyn M. Wahl, Christine A. Rees, and Keith E. Murphy. Retrotransposon insertion in SILV is responsible for merle patterning of the domestic dog. Proceedings of the National Academy of Sciences, 9 January 2006, 103(5):1376-81. Published on line. See also the commentary discussing the impact of this work by Richard Cordaux and Mark A. Batzer: Teaching an old dog new tricks: SINEs of canine genomic diversity. Proceedings of the National Academy of Sciences, 9 January 2006, 103(5):1157-8. The canine genome has been sequenced: K. Lindblad-Koh et al. Genome sequence, comparative analysis and haplotype structure of the domestic dog. Nature, 8 December 2005, doi:10.1038/nature04338. Copy available here.Publications and Presentations by George M. StrainClick here to see a list of publications by Dr. Strain "Prevalence of deafness in dogs heterozygous or homozygous for the merle allele." Journal of Veterinary Internal Medicine 2009, 23:282-286. © 2009 ACVIM. "Deafness in blue-eyed white cats: The uphill road to solving polygenic disorders." The Veterinary Journal 2007, 173:471-472 (PDF format). © 2007 Elsevier Ltd. Congreso Internacional de Medicina, Cirugia y Zootechnia en Perros, Gatos y otras Mascotas, Acapulco, Mexico, May, 2006. Sordera Hereditaria en Perros y Gatos (Hereditary Deafness in Dogs and Cats) (PDF format, 1.9M) Pruebas de Electrodiagnóstico Neurológico (Neurologic Electrodiagnostic Testing) (PDF format, 9.8M) "Deafness prevalence and pigmentation and gender associations in dog breeds at risk," The Veterinary Jouranl 167(1):23-32, 2004 (PDF format). © 2003 Elsevier Ltd. "Heritability and segregation analysis of deafness in U.S. Dalmatians," by EJ Cargill, TR Famula, GM Strain & KE Murphy. Genetics 166:1385-1393, 2004 (PDF format). © 2004 Genetics Society of America. "Hereditary deafness in dogs and cats: Causes, prevalence, and current research," Tufts' Canine and Feline Breeding and Genetics Conference, Old Sturbridge, MA. October, 2003. Conference PowerPoint presentation. "Congenital deafness and its recognition," Veterinary Clinics of North America - Small Animal Practice 29:895-907, 1999. © 1999 W.B. Saunders. "Aetiology, prevalence and diagnosis of deafness in dogs and cats." British Veterinary Journal 152:17-36, 1996. © 1996 Baillière Tindall. Deafness data analysis from: Strain, G.M. and B.L. Tedford. 1996. Deafness prevalence and associated phenotypic markers in dog breeds with high risk. Proc. 14th Ann. Vet. Med. Forum, ACVIM 14:772. San Antonio, May, 1996. Presented talk : Updated version of a talk (PowerPoint format) presented to Dalmatian clubs in Vienna, Amsterdam, and London in October, 1997, and to other groups since then.Other Information Bibliography of research publications related to Deafness in Dogs. Bibliography of research publications related to Deafness in Cats. Discussion of genetics of deafness. Editorial summarizing recently identified human & mouse genes related to deafness. Hereditary Hearing Loss home page - genes for deafness identified to date. Canine Inherited Disorders Database (CIDD) home page - Canadian source, information on all known canine genetic disorders. Inherited Diseases in Dogs home page (IDID) - similar listing from the U.K. Online Mendelian Inheritance in Animals (OMIA) - similar listings, multiple species. Book: Living With a Deaf Dog Book: Hear, Hear! A Guide to Training a Deaf Puppy Instructions on building a vibrating collar (originally posted on the Deaf Dog web page). Notes on Training With a Vibrating Collar. Sources (DDEAF) for electronic vibrating collars: (http://www.deafdogs.org/resources/vibramakers.php). Source for electronic vibration obedience training collars: Dogtra training collars (www.k9electronics.com/dogtra-training-collars/). Source for a GPS-based tracking device for dogs: dog tracking collars (www.k9electronics.com/dog-tracking-systems/). Loc8tor Handheld Pet Finder (http://www.k9electronics.com/loc8tor-pet-handheld-pet-finder.html). Source for a GPS-based tracking device for dogs: Garmin Astro (http://www.gpsnow.com/garmin_astro.htm). Dalmatian Club of America position statement regarding reducing deafness in the Dalmatian. Curriculum Vitae for Dr. Strain Search PubMed for publications by Dr. Strain Links to related web sitesGratitude is expressed to the following sources of research funding that have financially supported this research program: Dalmatian Club of America Chicagoland Dalmatian Club National Institute on Deafness and Other Communication Disorders, National Institutes of Health, US Public Health Service American Kennel Club Canine Health Foundation Jack Russell Terrier Research Foundation Louisiana State University School of Veterinary Medicine Individual donors  George M. Strain, PhD Professor of Neuroscience Department of Comparative Biomedical Sciences School of Veterinary Medicine Louisiana State University Baton Rouge, LA 70803 USA Phone: 225-578-9758 Fax: 225-578-9895 E-Mail: strain@lsu.edu The Deafness in Dogs & Cats home pagewas constructed by George M. Strain,to whom all comments should be addressed. The statements and opinions includedin this home page are those of the author only. Any statements and opinionsincluded in these pages are not those of Louisiana State University or theLSU Board of Supervisors.Awards Date last modified: 9/15/2011.You are visitor number  .Counter compliments of WebCounter.The Strain laboratory is an outstandingexample of how scientific studies can benefit the pet-owning public by addressingnervous sytem disorders, expanding our knowledge base, generate new avenuesof scientific inquiry and influencing how veterinarians think about thetreatment strategies they offer to clients. For nearly 30 years at LouisianaState University, we have been pursuing the line of research that examinescongenital deafness and other neurologic disorders in dogs, cats, and otherspecies. This has been an enormous, fascinating, rewarding, and ongoingendeavor that would not be possible without external financial and philanthropicsupport. We invite you to consider the Strain Lab as one of your top philanthropicpriorities. Please contact George Strain at 225-578-9758 or strain@lsu.eduto learn more about how a gift supporting our understanding of deafnessand reducing its impact can be made.Thispage and other pages are © Copyright 1996 - 2010 by George M. Strainexcept where other copyrights apply. LSUHome PageLSU School of Veterinary Medicine HomePage |
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Information | about | the | condition, | including | an | article | describing | the | association | of | congenital | deafness | with | white | coat | color. |
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